According to an article on Yahoo.com entitled Study: Long Commute Could Lead To Divorce, Separation, a new study out of Sweden suggests that long commutes increase chances of a divorce by 40 percent. This study found that the impact of a long commute tends to be higher on women than on men and that the riskiest time for a divorce is during the first few years of the long commute.
Obviously, there is no one factor which is a perfect predictor of divorce. Other factors can include things like just the opposite: transitioning to working from home after the couple is used to working outside of the house.